*New*
 Rigged trials
 Legal Letter
 GM Crops: Risks and Risk Management Required
 Agronomics and Economics of GM Canola

1. Key issues
 Summary and Overview
 10 main NCF concerns
 Farmers misled
 Q & A for school projects
 What is the drive for GM crops?
 Links to other issues
 Scientific concerns summary
 The future - 2020?
 What is expected of non-GM growers in Canada
 Beyond the Bulldust
 *Unfair liability*
 Pressures in GM debate
 Questions regarding risk management
 Genetic engineering – a crop of hyperbole
 Agronomics and Economics of GM canola

2. GM crops banned
 Monsanto Crop Management & Resistance Management Plans
 Why Australia is not prepared for commercial trials
 Monsanto's GM Roundup Ready canola
 Bayer Cropscience's GM Invigor canola
 Where to now?
 State legislation - moratoria

3. Market issues
 Canola markets
 Zero tolerance of GM contamination is market demand
 Wheat will be impacted
 Higher prices for non-GM canola
 Contamination scare affects market
 Japanese requirements
 Consumer polls & market rejection
 Effects of GM contamination in canola
 EU will not tolerate acceptance of tolerance levels
 What our marketers say
 How and when non-GM premiums started

About us
 Network Policy & Objectives
 NCF Funding
 NCF History
 NCF profile: Julie Newman
 NCF profile: Juliet McFarlane
 Early work

Canola
 What is canola?
 Statistics - yields
 GM Canola Factsheet
 Canadian farmers nervous about GM canola acceptance in Japan
 Letter from Japan

Coexistence & Segregation
 Crop Management Plans for non-GM grower
 Farmer to farmer Hypothetical
 Segregation and coexistence plans
 Seed industry allows 0.5% contamination
 Canadian grain segregation
 Zero tolerance is market demand
 European coexistence report
 Identity preservation and segregation
 What is expected of non-GM growers in Canada
 Testing protocol
 Labels for GM contamination
 EU will not accept contamination
 Proposed Stewardship Program for Canola
 Contract harvester problems
 Crop management plans
 Industry avoids the truth about GM segregation

Consumer concerns
 Is GM food safe?
 Churches - 10 reasons against GM
 Scientific concerns
 Cross Kingdom Breeding
 Food safety testing inadequate
 Environmental effects
 13 Science based reasons for GM-free
 Myths about the Digestion of Proteins and DNA
 5 part series covering issues
 Health Risk
 Reason for Schools to ban GM Foods
 Monsanto's feeding studies
 FSANZ answers regarding food testing
 Scientific report on safety testing
 Trespass report
 Scientific concerns
 Consumer concerns summary
 GM food lecture
 Monsanto
 Seeds of Concern
 Public attitudes to GM food
 Scrambling and gambling with the genome
 L-tryptophan - A Deadly Epidemic
 Protestors (photos)
 GM health concerns in brief
 Inadequate health testing for GM canola
 Russian study showing high death rates in offspring
 Pusztai debate
 Hidden uncertainties - risks of GMOs
 Study shows GM eating Americans sicker than non-GM eating English
 Scientists see spike in kids' food allergies
 Latest GMO Research: Decreased Fertility, Immunological Alterations and Allergies
 Key health papers of concern
 Do we really know what we are doing?

Contamination
 Contamination is uncontrollable (photos)
 Gene transfer & cross-pollination
 GM product recalls
 Environmental contamination (photos)
 Confronting contamination & co-existence
 Invigor canola outcrossing
 Gene Stacking = Super Weed
 AOF contamination report
 History of how Bayer Cropscience caused contamination of non-GM canola in Australia
 Fighting GMO contamination around the world

Corporate control
 Corporate control
 Corporate Engineering in Public Debate
 Commercial influence on science
 In (Seed) Bed Together
 The drive behind GM Crops
 Cartoon
 IP And Genetically Modified Organisms: A Fateful Combination
 Commercial influence on science
 Made by Monsanto

Costs and liabilities
 Costs to non-GM farmers
 Non-GM Liable for Contamination?
 Liability issues associated with GM crops - AFFA
 Supplying non-GM requires certification
 Liability questions answered
 More on liability
 *Farmer liability*
 Liability and GM crops

Economics
 No economic benefit for farmers
 Economic Recommendations
 Economic Critique
 Why has the OGTR ignored economics?
 Australian farmers can not afford GM crops
 What benefit?
 Higher plant yields better or worse for farmers?
 Effects of GM contamination in canola
 Global seed industry concentration
 Canada versus Australia comparison
 No farmer economic gain for pharmaceutical crops
 NCF: Economics of GM canola ***
 Agronomics and Economics of GM Canola

Farmer attitudes
 Australian farmer surveys
 Farm lobby group policies
 Victorian ALP policy
 GCA farm lobby group policies

GM / Non-GM difference
 What is GM / Non-GM?
 GM plant breeding not faster
 Will the industry be in crisis without GM?
 Why GM is different
 Non-GM biotech is the future

GM canola
 Will GM canola yield more in Australia?
 Comparison between Canadian and Australian canola conditions
 Are GM chemicals safer, cheaper or more efficient?
 How much GM canola is grown in Canada?
 Canadian and Australian canola statistics
 Economics of GM canola

GM crops
 Public good or corporate control?
 Misleading claims over GM
 ISAAA GM crop areas misleading
 Use of GM crops
 GM crops and chemical use
 Multiple spray applications vs yield penalty
 Yield problems - links
 GM cotton failures
 Global yields
 Pharmaceutical crops
 Global Trends in GM Crops
 Who benefits from GM crops?

GM crops experience
 Canadian Farmers viewpoint
 American farmers viewpoint
 American Corn Growers experience
 Argentina faces serious problems
 Report on North American Experience
 Canadian organic farmers
 Argentina & GM soy - success at what cost?
 How is industry managing non-GM now?
 India, Bulgaria, Indonesia
 Monsanto vs US farmers
 Global GM adoption
 US farmers warned of GM Liability
 Farming news links
 GM-growing US faces agricultural trade deficit
 GM soy in US not considered food grade
 Monsanto in Argentina
 GM soy war in Paraguay
 Violence in Brazil
 12 Years of GM soya in Argentina - disaster for people and environment

GM wheat
 Learn more about GM wheat
 Marketing systems for GM wheat
 GM Wheat submission - food health
 Report - Farmers lose with GM wheat
 What our marketers say
 Canadian Wheat Board position
 GM Wheat impossible to segregate

Honey issues
 Apiarist briefing
 The impact of GM contamination
 SA Apiarists briefing
 Map SA & Vic
 Honey tests reveal GM contamination

How trustworthy is decision-making?
 Vested interests revealed
 Why trust the regulatory process?
 Sue Meek profile
 Federal government pro-GM
 Scientists influenced
 Liability, GCA and legal action
 Research manipulated
 OGTR does not assess economics, segregation, chemical resistance, food testing etc.
 Three faces of science fraud
 Misleading GM language

Insurance
 Insurance Council submission
 Insurance avoid GM risk

International Protocols
 World Trade Organisation
 Cartagena Protocol on Biosafety
 Free Trade Agreement
 Farmers right to replant seeds
 International agreements
 GM labelling
 WTO ruling does not prevent countries from restricting or banning GMOs
 Biotechnology Policy Documents of FAO Members

Legal Issues
 Law
 Copy of Technology User Agreement
 2003 Monsanto contract
 GM Patents
 Monsanto shoot themselves in the foot (cartoon)
 Will law protect us from contamination?
 Summary of Supreme Court hearing of Percy Schmeiser
 NSW Minister guarantees farmers are protected
 AFFA-liability issues
 US farmers sued
 US farmers warned of GM liability issues
 GM Crops and farmers Liability
 Why is the non-GM grower liable for contamination?
 Innocent farmer sued
 Federal judge's opinion shows understanding of patented gene spread
 Liability for non-GM farmers
 More on liability:
 Liability and GM crops
 Farmers prepare for legal fight over GM
 Legal letter from non-GM to GM
 Liability issues - Duncan Currie

Legislation & Regulation
 Trials vs Commercial Release
 Bayer Cropscience Invigor Canola approved by OGTR
 States impose moratoriums in role to protect economics
 OGTR role
 Gene Technology Act
 GM canola trial locations
 Victorian Moratorium
 Australian GM status by States
 Federal candidate views
 OGTR unapproved GM canola trials
 Gene Technology Act Critique
 South Australian Act
 WA proudly GM-free
 *State moratoria legislation*
 Gene Tech Act reviews denies compensation
 National Biotechnology Strategy
 Chronology of genetic engineering regulation in Australia: 1953–2008

Links
 Genome Scrambling Links
 Links
 Top 10 books on GM
 Religious links

Network action
 Invigor canola submission OGTR
 GM Zone proposal submissions
 GTGC submission summary
 NCF Newsletters
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 GTGC full submission
 Roundup Ready Submission OGTR
 Network tours
 pro-GM lobbyists attack NCF
 Pro-GM tantrums
 Advertisement
 Victorian farmer survey
 NCF banner & flyer
 Field day survey
 Community monitoring of GM Crop Trials
 Letters to farmers
 
 Gene Tech Act Review Pt1
 Gene Tech Act Reveiw Pt 2
 Gene Tech Act Review Pt3
 Bayer Protest
 Bayers Response to NCF
 NCF submission released

Organics
 Canadian organic standard
 American organic standards

Trials
 Victorian maps
 Victorian sites - photos
 SA trial photos
 Trials summary
 Topas 19/2 contamination
 South Australia 2006 GM Trials

 

13 December 2003

Scientific concerns

Furphy: "GM rejection is based on unscientific and unfounded fears." Many scientists disagree with this statement.

Genetically Modified Foods are Inherently Unsafe, by Jeffrey M. Smith (Author)

Assumption Actual Status Quote
Inserted genes will produce a single protein. Inserted foreign genes might create multiple proteins, with unpredictable consequences. “The fact that one gene can give rise to multiple proteins . . . destroys the theoretical foundation of a multibillion-dollar industry, the genetic engineering of food crops.” Dr. Barry Commoner, senior scientist at the Center for the Biology of Natural Systems at Queens College
The proteins created by inserted genes will act exactly the same way in a new organism. Foreign proteins may be folded improperly or become attached to other molecules, which could change their properties. Likewise, gene expression may be affected by the genetic disposition of a host organism, or even the environment. Dr. Peter Wills of Auckland University warns, “an incorrectly folded form of an ordinary cellular protein can under certain circumstances . . . [duplicate itself] and give rise to infectious neurological disease.” Professor David Schubert of The Salk Institute for Biological Studies, says the effect that a particular protein has on a plant or animal “can be modified by the addition of molecules such as phosphate, sulfate, sugars, or lipids.”
Inserting foreign genes is precise and non-disruptive. The process of inserting foreign genes can damage the structure and function of the host’s DNA, switch genes on or off, create never-before-seen genetic sequences, and render the genome unstable. The BBC’s Tomorrow’s World Magazine says: “Genetic engineering is generally a hit and miss affair. The genes may be inserted the wrong way round or multiple copies may be scattered throughout a plant’s genome. They may be inserted inside other genes—destroying their activity or massively increasing it. More worryingly, a plant’s genetic make-up may become unstable. . . . Rogue toxins may be produced or existing ones amplified massively. Such problems may only arise hundreds of generations after the crops are originally modified.”
Foreing genes will not transfer to bacteria in the digestive system. Use of antibiotic resistant genes are therefore safe. Foreign genes jumped to human gut bacteria in just one meal of a GM soy burger and soy milkshake. "British scientific researchers have demonstrated for the first time that genetically modified DNA material from crops is finding its way into human gut bacteria, raising potentially serious health questions." The Guardian In 1992, Murray Lumpkin, M.D., then director the FDA’s Division of Anti-infective Drug Products, warned: “IT WOULD BE A SERIOUS HEALTH HAZARD TO INTRODUCE A GENE THAT CODES FOR ANTIBIOTIC RESISTANCE INTO THE NORMAL FLORA OF THE GENERAL POPULATION.”
The promoter that keeps foreign genes switched on, only influences that one gene. The promoter may turn on native genes “over long distances” up and down the strand of DNA—even genes on a different chromosome. This can create a flood of proteins with unpredictable consequences. Some scientists theorize that the promoter might even switch on dormant viruses that are deposited along the DNA. “When inserted into another organism as part of a 'genetic construct,' it [the promoter] may also change the gene expression patterns in the recipient chromosome(s) over long distances up- and downstream from the insertion site.” Dr. Michael Hansen, Consumers Union, publishers of Consumer Reports And in their paper, “Cauliflower Mosaic Viral Promoter—A Recipe for Disaster,” Drs. Ho, Ryan, and Cummins warn, “Horizontal transfer of the CaMV promoter . . . has the potential to reactivate dormant viruses or [create] new viruses in all species to which it is transferred.”
The promoter is stable. Studies indicate that the promoter may create a “hotspot” in the DNA, whereby the whole DNA section, or chromosome, can become unstable. This can cause breaks in the strand or exchanges of genes with other chromosomes. According to Geneticist Dr. Joe Cummins, a promoter can have “the same impact as a heavy dose of gamma radiation.”
The promoter only works with plant organisms. Research indicates that the promoter can influence animal genes. Some scientists believe it can transfer to internal organs and accelerate cell growth, possibly leading to cancer. Dr. Stanley Ewen, one of Scotland’s leading experts in tissue diseases, says, "It is possible GM DNA could affect stomach and colonic lining by causing a growth factor effect with the unproven possibility of hastening cancer formation in those organs."
Nutritional properties are unaffected by genetic modification. Significant differences in nutritional content between GM crops and their natural counterparts have been observed. “Roundup Ready beans were significantly lower in protein and the amino acid phenylalanine. More disturbing were [increased] levels of the allergen trypsin inhibitor in toasted Roundup Ready meal. . . . Lectins in Roundup Ready beans almost doubled the levels in controls. What might be the result of consuming foods with high levels of trypsin inhibitor and lectin? Well, maybe slower and lower growth, say scientists.” Medical writer Barbara Keeler, on data that hasd been omitted from Monsanto’s published study.
Genes and their expression will act in isolation, not impacting other metabolic processes. Insertion of foreign genes and their new proteins may create complex, unpredictable interactions, not well understood. Similarly, inserting two or more foreign genes into the same plant may also cause interactions that have not been studied. University of Georgia’s Dr. Sharad Phatak says, “When you insert a foreign gene, you are changing the whole metabolic process. . . Each change is going to have an effect on other pathways. Will any one gene kick off a whole slew of changes? We don’t know for sure.” Stanford’s Dr. Charles Yanofsky says, “Genetic engineering results in the formation of higher than normal concentrations of certain enzymes and products; these could provide the basis for the synthesis of higher levels of toxic substances.” Commenting on the genetically modified supplement L-tryptophan produced by Showa Denko, which killed about 100 people and caused 5-10,000 to fall sick, Yanofsky, one of the world's leading authorities on tryptophan biosynthesis, says, “If Showa Denko engineered the bacterium to overproduce tryptophan [which they did], then there are many unknowns that would be associated with its overproduction.”
There is no risk from breathing pollen from GM crops If GM genes can transfer to gut bacteria or internal organs, then inhalation of pollen may cause unpredicted health problems. “Experts on the Government's Advisory Committee on Novel Foods and Processes have issued a warning about plants being grown in the U.S. and parts of Europe which contain a gene resistant to antibiotics. They are concerned that, if workers breathe in dust as the crops are processed, the resistance could be transferred to bacteria in their throats. Around one in five people are carriers of the meningitis bacteria, even though they are not affected by the disease. Microbiologist Dr. John Heritage, a member of the committee, has written to American authorities to express his worries. 'It's a huge concern to me,' he said. 'While the risk is small, the consequences of an untreatable, life-threatening infection spreading within the population are enormous.'” Daily Mail (UK)
The chances of GM crops being allergenic are minimal. After GM soy was introduced into the UK, soy allergies skyrocketed 50%. Current GM corn would not pass tests recommended by international Codex standards for potential allergenicity. It took the FDA 9 months to develop an allergy test for StarLink corn; It was so poorly designed, however, that the EPA's Scientific Advisory Panel rejected its results. The FDA’s 1992 policy states, “At this time, FDA is unaware of any practical method to predict or assess the potential for new proteins in food to induce allergenicity and requests comments on this issue.” FDA scientist Dr. Carl Johnson wrote, “Are we asking the crop developer to prove that food from his crop is non-allergenic? This seems like an impossible task.” According to FDA microbiologist Dr. Louis Pribyl, “the only definitive test for allergies is human consumption by affected peoples, which can have ethical considerations.” According to a 1999 Washington Post article, there is still “no widely accepted way to predict a new food’s potential to cause an allergy. The FDA is now five years behind in its promise to develop guidelines for doing so.” The same remains true today.

Yes! Books, P.O. Box 469, Fairfield, Iowa 52556
Tel: 888-717-7000, 641-472-2536 Fax: 888-FAX-7000 (888-329-7000) info@seedsofdeception.com info@seedsofdeception.com info@seedsofdeception.com Source: "Seeds of Deception" by Jeffrey Smith (here)

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Practical risk found and practical solutions to hide it:

Details on Arnold Puztai's research (leading UK scientist): Extract from "Seeds of deception" Jeffrey M. Smith

"What Pusztai and his team found was quite a shock. First, the nutritional content of some GM potatoes were considerably different from their non-GM parent lines, even though they were grown in identical conditions. One GM potato line, for example, contained 20 % less protein that its own parent line. Second, even the nutritional content of sibling GM potatoes, offspring of the same parent grown in identical conditions, was significantly different.

If Pusztai’s results were limited to just these facts, they alone might have undermined the entire regulatory process of GM foods. FDA policy was based on the assumption that genetically modified foods were stable. Nutrient levels were not supposed to vary.

But these findings were completely eclipsed by Pusztai’s other, more disturbing discoveries. He found that rats which were fed GM potatoes suffered damaged immune systems. Their white blood cells responded much more sluggishly than those fed a non-GM diet, leaving them more vulnerable to infection and disease. Organs related to the immune system, the thymus and spleen, showed some damage as well.

Compared to rats fed a non-GM control diet, some of the GM fed rats had smaller, less developed brains, livers, and testicles. Other rats had enlarged tissues, including the pancreas and intestines. Some showed partial atrophy of the liver. What’s more, significant structural changes and a proliferation of cells in the stomach and intestines of GM-fed rats may have signaled an increased potential for cancer.

The rats developed these serious health effects after only ten days. Some of these changes persisted after 110 days, a time period corresponding to about 10 years of human life.

In preparing the diet, Pusztai had been characteristically thorough. Comparisons had been made between rats fed GM pototates, natural potatoes, and natural potatoes spiked with the same amount of pure lectin as found in the GM potato. The researchers varied the potato preparation, using raw, boiled and baked potatoes, and varied the amounts in the diet. They also varied the total protein content of the diets and tested all these variations over both 10 day and 110-day periods. These testing protocols had all been thoroughly scrutinized and approved in advance by the government’s funding office and were consistent with several published studies.

In the end only the rats that ate the GM potatoes suffered the serious negative effects. From the evidence, it was clear that the lectins were not the major cause of the health damage. Rather, there was some effect from the process of genetic engineering itself that caused the damaged organs and immune dysfunction of the adolescent rats. "We used exactly the same methods of genetic engineering as used by the food companies," says Pusztai.

Pusztai knew that his results strongly suggested that the GM foods already approved and being eaten by hundreds of millions of people every day might be creating similar health problems in people, especially in children. (pg 12)

"… I find it is very, very unfair to use our fellow citizens as guinea pigs. We have to find the guinea pigs in the laboratory." (pg 15)

"The next day the Pusztais came to work encouraged that the truth would finally get out. When they were called to a meeting, Arpad Pusztai expected to be handed the corrected release for review. But when he entered the room, the whole top management was assembled. Professor James spoke in a manner that was quite different from that of the previous day. In fact, the Pusztais had never heard him speak that way before.

He said I was to be suspended, and they will have an audit of the whole business, and then I shall be made to retire, recounts Pusztai. And my retiring wasn’t dependent on what the audit found." pg 18

"James did not act alone. He handpicked a panel of scientists to conduct an audit of Pusztai’s work. It was quite telling that the scientists he selected were not working nutritionists. "That a nutritional institute should select non-nutritionists to do this audit is quite unbelievable," says Pusztai. Moreover, the panel was not given the complete data, did their entire review in less than a day, and didn’t consult with Pusztai at all.

A summary of their audit report was released on October 28. It claimed that there were important deficiencies in Pusztai’s study. The full audit report, however, was never publicly released. To prevent leaks, only ten copies were printed. Even the chairman of the panel that produced the report was not given a copy." pg 22

"A report published two days later exposed the fact that Monsanto had given the Rowett Institute 140,000pounds before the blow-up, adding even more fuel to the media’s fire." pg 23

"A lot of energy was being spent attacking and defending viewpints. Very little energy was spent on safety testing.

It would have been fairly straightforward to conduct a follow-up study on Pusztai’s research to find out, for example, if any of the GM products we were eating create similar organ or immune system problems. But, having seen what happened to Pusztai, no one was willing to go there.

The British government clearly wasn‘t. According to one observer from the UK‘s Natural Law Party, the reason the government had commissioned the research team from the Rowett Institute " in the first place was that it was convinced that it would come up with a favorable result in relation to the safety of the GM potatoes… In fact, after Pusztai‘s unexpected discovery, the British government ended all funding in safety testing." pg 33

"According to a March 2001 article in the New York Times, "The CDC (Centre for Disease Control) now says that food is responsible for twice the number of illnesses in the United States as scientists thought just seven years ago... At least 80% of food-related illnesses are caused by viruses or other pathogens that scientists cannot even identify." The reported cases include 5,000 deaths, 325,000 hospitalizations, and 76 million illnesses per year. This increase roughly corresponds to the period when Americans have been eating GM food. In addition, obesity has skyrocketed. In 1990, no state had 15% or more of its population in the obese category. By 2001, only one state didn't. Diabetes rose by 33% from 1990 to 1998, lyphatic cancers are up, and many other illnesses are on the rise. Is there a connection to GM foods? We have no way of knowing because no one has looked for one.

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Other references can be found:  http://www.biotech-info.net/new.html

*Genetically Modified Foods: Are They a Risk to Human/Animal Health? by Arpad Pusztai, Ph.D., An actionbioscience.org original article

*Science as Culture (draft) The Pusztai Controversy: editorial introduction, October 7, 2001

*Submission by Stanley Ewen (M.B.Ch.B., Ph.D., F.R.C.Path) to the Health Committee of the Scottish Parliment in response to their investigation into the health impact of GM crops.

*Submission of evidence to the Clerk to the Health and Community Care Committee of  The Scottish Parliament from Dr. Árpád Pusztai's Submission to the Scottish Parliment

*Can Science Give Use the Tools for Recognizing Possible Health Risks From GM Foods? by Dr. Arpad Pusztai, in Nutrition and Health, 2002, Volume 16, pp. 73-84

*Dr. Pusztai's PowerPoint Presentation: GM FOOD/FEED: GAPS IN RISK-ASSOCIATED RESEARCH THAT NEED TO BE FILLED, presented at the Denver Conference

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25 February 2004

New health dangers of GM food discovered

- 1. Bt-maize (Dekalb 818 YG), during pollination, may have triggered disease in people living near the maize field in the Philippines.
2. The cauliflower mosaic virus (CaMV) promoter, used in most GM foods, was found intact in rat tissues two hours, six hours, and three days after it was mixed into a single meal, and was also confirmed to be active in human cells.
3. Genetically engineered pox viruses in cell cultures recombined with natural viruses to create new hybrid viruses with unpredictable and potentially dangerous characteristics.

More (here)

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09 November 2009
Industry avoid the truth about GM segregation problems

11 June 2009
Dupont alleges anti-competitive conduct by Monsanto

24 February 2009
Non-GM Farmers to pay for unwanted GM contamination

02 February 2009
Made by Monsanto

01 February 2009
Top 10 Seed and Pesticide companies

29 January 2009
Agronomics and Economics of GM Canola

29 January 2009
Non-GM biotech is the future

26 January 2009
12 Yrs of GM soya in Argentina - disaster for people and environment

19 January 2009
Non-GM seed preferred by farmers but difficult to obtain

16 January 2009
GM Canola a flop

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